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Integration of longitudinal deep-radiomics and clinical data improves the prediction of durable benefits to anti-PD-1/PD-L1 immunotherapy in advanced NSCLC patients

BACKGROUND: Identifying predictive non-invasive biomarkers of immunotherapy response is crucial to avoid premature treatment interruptions or ineffective prolongation. Our aim was to develop a non-invasive biomarker for predicting immunotherapy clinical durable benefit, based on the integration of r...

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Detalles Bibliográficos
Autores principales: Farina, Benito, Guerra, Ana Delia Ramos, Bermejo-Peláez, David, Miras, Carmelo Palacios, Peral, Andrés Alcazar, Madueño, Guillermo Gallardo, Jaime, Jesús Corral, Vilalta-Lacarra, Anna, Pérez, Jaime Rubio, Muñoz-Barrutia, Arrate, Peces-Barba, German R., Maceiras, Luis Seijo, Gil-Bazo, Ignacio, Gómez, Manuel Dómine, Ledesma-Carbayo, María J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9985838/
https://www.ncbi.nlm.nih.gov/pubmed/36872371
http://dx.doi.org/10.1186/s12967-023-04004-x