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Discovery of novel DNA‐damaging agents through phenotypic screening for DNA double‐strand break
DNA double‐strand breaks (DSBs) seriously damage DNA and promote genomic instability that can lead to cell death. They are the source of conditions such as carcinogenesis and aging, but also have important applications in cancer therapy. Therefore, rapid detection and quantification of DSBs in cells...
Autores principales: | Zhang, Doudou, Shimokawa, Takashi, Guo, Qianqian, Dan, Shingo, Miki, Yoshio, Sunada, Shigeaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986057/ https://www.ncbi.nlm.nih.gov/pubmed/36385507 http://dx.doi.org/10.1111/cas.15659 |
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