Human EGFRvIII chimeric antigen receptor T cells demonstrate favorable safety profile and curative responses in orthotopic glioblastoma

OBJECTIVES: Glioblastoma is a highly aggressive and fatal brain malignancy, and effective targeted therapies are required. The combination of standard treatments including surgery, chemotherapy and radiotherapy is not curative. Chimeric antigen receptor (CAR) T cells are known to cross the blood–bra...

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Detalles Bibliográficos
Autores principales: Abbott, Rebecca C, Iliopoulos, Melinda, Watson, Katherine A, Arcucci, Valeria, Go, Margareta, Hughes‐Parry, Hannah E, Smith, Pete, Call, Melissa J, Cross, Ryan S, Jenkins, Misty R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986233/
https://www.ncbi.nlm.nih.gov/pubmed/36890859
http://dx.doi.org/10.1002/cti2.1440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986233/
https://www.ncbi.nlm.nih.gov/pubmed/36890859
http://dx.doi.org/10.1002/cti2.1440

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