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Phosphorylation of PHF2 by AMPK releases the repressive H3K9me2 and inhibits cancer metastasis

Epithelial to mesenchymal transition (EMT) plays a crucial role in cancer metastasis, accompanied with vast epigenetic changes. AMP-activated protein kinase (AMPK), a cellular energy sensor, plays regulatory roles in multiple biological processes. Although a few studies have shed light on AMPK regul...

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Detalles Bibliográficos
Autores principales: Dong, Ying, Hu, Hao, Zhang, Xuan, Zhang, Yunkai, Sun, Xin, Wang, Hanlin, Kan, Weijuan, Tan, Min-jia, Shi, Hong, Zang, Yi, Li, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986243/
https://www.ncbi.nlm.nih.gov/pubmed/36872368
http://dx.doi.org/10.1038/s41392-022-01302-6