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Connection between MHC class II binding and aggregation propensity: The antigenic peptide 10 of Paracoccidioides brasiliensis as a benchmark study

The aggregation of epitopes that are also able to bind major histocompatibility complex (MHC) alleles raises questions around the potential connection between the formation of epitope aggregates and their affinities to MHC receptors. We first performed a general bioinformatic assessment over a publi...

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Detalles Bibliográficos
Autores principales: Ochoa, Rodrigo, Cardim-Pires, Thyago R., Sant’Anna, Ricardo, Cossio, Pilar, Foguel, Debora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986244/
https://www.ncbi.nlm.nih.gov/pubmed/36890879
http://dx.doi.org/10.1016/j.csbj.2023.02.031