Serum/glucocorticoid-inducible kinase 1 deficiency induces NLRP3 inflammasome activation and autoinflammation of macrophages in a murine endolymphatic hydrops model

Ménière’s disease, a multifactorial disorder of the inner ear, is characterized by severe vertigo episodes and hearing loss. Although the role of immune responses in Ménière’s disease has been proposed, the precise mechanisms remain undefined. Here, we show that downregulation of serum/glucocorticoi...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Dao-Gong, Yu, Wen-Qian, Liu, Jia-Hui, Kong, Li-Gang, Zhang, Na, Song, Yong-Dong, Li, Xiao-Fei, Fan, Zhao-Min, Lyu, Ya-Feng, Li, Na, Wang, Hai-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986248/
https://www.ncbi.nlm.nih.gov/pubmed/36872329
http://dx.doi.org/10.1038/s41467-023-36949-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986248/
https://www.ncbi.nlm.nih.gov/pubmed/36872329
http://dx.doi.org/10.1038/s41467-023-36949-4

Ejemplares similares