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Elimination of enzymes catalysis compartmentalization enhancing taxadiene production in Saccharomyces cerevisiae

Taxadiene is an important precursor in taxol biosynthesis pathway, but its biosynthesis in eukaryotic cell factories is limited, which seriously hinders the biosynthesis of taxol. In this study, it is found that there was the catalysis compartmentalization between two key exogenous enzymes of gerany...

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Detalles Bibliográficos
Autores principales: Zhang, Chenglong, Chen, Wang, Dong, Tianyu, Wang, Ying, Yao, Mingdong, Xiao, Wenhai, Li, Bingzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986319/
https://www.ncbi.nlm.nih.gov/pubmed/36890913
http://dx.doi.org/10.3389/fbioe.2023.1141272