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Vinculin strengthens the endothelial barrier during vascular development

Remodelling of cell–cell junctions is crucial for proper tissue development and barrier function. The cadherin-based adherens junctions anchor via β-catenin and α-catenin to the actomyosin cytoskeleton, together forming a junctional mechanotransduction complex. Tension-induced conformational changes...

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Detalles Bibliográficos
Autores principales: van der Stoel, Miesje M, Kotini, Maria P, Schoon, Rianne M, Affolter, Markus, Belting, Heinz-Georg, Huveneers, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bioscientifica Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986378/
https://www.ncbi.nlm.nih.gov/pubmed/36260739
http://dx.doi.org/10.1530/VB-22-0012