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Vinculin strengthens the endothelial barrier during vascular development
Remodelling of cell–cell junctions is crucial for proper tissue development and barrier function. The cadherin-based adherens junctions anchor via β-catenin and α-catenin to the actomyosin cytoskeleton, together forming a junctional mechanotransduction complex. Tension-induced conformational changes...
Autores principales: | van der Stoel, Miesje M, Kotini, Maria P, Schoon, Rianne M, Affolter, Markus, Belting, Heinz-Georg, Huveneers, Stephan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Bioscientifica Ltd
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986378/ https://www.ncbi.nlm.nih.gov/pubmed/36260739 http://dx.doi.org/10.1530/VB-22-0012 |
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