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A common genetic variation in GZMB may associate with cancer risk in patients with Lynch syndrome

Lynch syndrome (LS), also known as hereditary nonpolyposis colorectal cancer syndrome (HNPCC) is a common genetic predisposition to cancer due to germline mutations in genes affecting DNA mismatch repair. Due to mismatch repair deficiency, developing tumors are characterized by microsatellite instab...

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Detalles Bibliográficos
Autores principales: Grolmusz, Vince Kornél, Nagy, Petra, Likó, István, Butz, Henriett, Pócza, Tímea, Bozsik, Anikó, Papp, János, Oláh, Edit, Patócs, Attila
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986427/
https://www.ncbi.nlm.nih.gov/pubmed/36890824
http://dx.doi.org/10.3389/fonc.2023.1005066