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Therapeutic targets for inflammatory bowel disease: proteome-wide Mendelian randomization and colocalization analyses

BACKGROUND: Identifying new drug targets for inflammatory bowel disease (IBD) is urgently needed. The proteome is a major source of therapeutic targets. We conducted a proteome-wide Mendelian randomization (MR) and colocalization analyses to identify possible targets for IBD. METHODS: Summary-level...

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Detalles Bibliográficos
Autores principales: Chen, Jie, Xu, Fengzhe, Ruan, Xixian, Sun, Jing, Zhang, Yao, Zhang, Han, Zhao, Jianhui, Zheng, Jie, Larsson, Susanna C., Wang, Xiaoyan, Li, Xue, Yuan, Shuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986512/
https://www.ncbi.nlm.nih.gov/pubmed/36857861
http://dx.doi.org/10.1016/j.ebiom.2023.104494