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Therapeutic targets for inflammatory bowel disease: proteome-wide Mendelian randomization and colocalization analyses
BACKGROUND: Identifying new drug targets for inflammatory bowel disease (IBD) is urgently needed. The proteome is a major source of therapeutic targets. We conducted a proteome-wide Mendelian randomization (MR) and colocalization analyses to identify possible targets for IBD. METHODS: Summary-level...
Autores principales: | Chen, Jie, Xu, Fengzhe, Ruan, Xixian, Sun, Jing, Zhang, Yao, Zhang, Han, Zhao, Jianhui, Zheng, Jie, Larsson, Susanna C., Wang, Xiaoyan, Li, Xue, Yuan, Shuai |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986512/ https://www.ncbi.nlm.nih.gov/pubmed/36857861 http://dx.doi.org/10.1016/j.ebiom.2023.104494 |
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