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Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin

Glucose transporters are gatekeepers of cellular glucose metabolism. Understanding how their activity is regulated can provide insight into mechanisms of glucose homeostasis and diseases arising from dysregulation of glucose transport. Glucose stimulates endocytosis of the human glucose transporter...

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Detalles Bibliográficos
Autores principales: Qualls-Histed, Susan J., Nielsen, Casey P., MacGurn, Jason A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986520/
https://www.ncbi.nlm.nih.gov/pubmed/36890792
http://dx.doi.org/10.1016/j.isci.2023.106150