Promotion of colorectal cancer by transcription factor BHLHE40 involves upregulation of ADAM19 and KLF7

BHLHE40 is a transcription factor, whose role in colorectal cancer has remained elusive. We demonstrate that the BHLHE40 gene is upregulated in colorectal tumors. Transcription of BHLHE40 was jointly stimulated by the DNA-binding ETV1 protein and two associated histone demethylases, JMJD1A/KDM3A and...

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Detalles Bibliográficos
Autores principales: Sui, Yuan, Jiang, Hanlin, Kellogg, Collyn M., Oh, Sangphil, Janknecht, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986587/
https://www.ncbi.nlm.nih.gov/pubmed/36890812
http://dx.doi.org/10.3389/fonc.2023.1122238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986587/
https://www.ncbi.nlm.nih.gov/pubmed/36890812
http://dx.doi.org/10.3389/fonc.2023.1122238

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