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Interleukin-27-dependent transcriptome signatures during neonatal sepsis

Human newborns exhibit increased vulnerability and risk of mortality from infection that is consistent with key differences in the innate and adaptive immune responses relative to those in adult cells. We have previously shown an increase in the immune suppressive cytokine, IL-27, in neonatal cells...

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Detalles Bibliográficos
Autores principales: Povroznik, Jessica M., Akhter, Halima, Vance, Jordan K., Annamanedi, Madhavi, Dziadowicz, Sebastian A., Wang, Lei, Divens, Ashley M., Hu, Gangqing, Robinson, Cory M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986606/
https://www.ncbi.nlm.nih.gov/pubmed/36891292
http://dx.doi.org/10.3389/fimmu.2023.1124140