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Protein interactors of 3-O sulfated heparan sulfates in human MCI and age-matched control cerebrospinal fluid

Heparan sulfates (HS) proteoglycans are commonly found on the cell surface and mediate many processes. Binding of HS ligands is determined by the sulfation code on the HS chain that can be N-/2-O/6-O- or 3-O-sulfated, generating heterogenous sulfation patterns. 3-O sulfated HS (3S-HS) play a role in...

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Detalles Bibliográficos
Autores principales: Ferreira, Andreia, Timmerman, Evy, Staes, An, Vuylsteke, Marnik, De Muynck, Louis, Gevaert, Kris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986659/
https://www.ncbi.nlm.nih.gov/pubmed/36879013
http://dx.doi.org/10.1038/s41597-023-02009-1