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The Rab GTPase-binding protein EHBP1L1 and its interactors CD2AP/CIN85 negatively regulate the length of primary cilia via actin remodeling

Primary cilia are organelles consisting of axonemal microtubules and plasma membranes, and they protrude from the cell surface to the extracellular region and function in signal sensing and transduction. The integrity of cilia, including the length and structure, is associated with signaling functio...

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Detalles Bibliográficos
Autores principales: Iwano, Tomohiko, Sobajima, Tomoaki, Takeda, Sén, Harada, Akihiro, Yoshimura, Shin-ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986712/
https://www.ncbi.nlm.nih.gov/pubmed/36754282
http://dx.doi.org/10.1016/j.jbc.2023.102985