T cell‐dependent bispecific antibodies alter organ‐specific endothelial cell–T cell interaction

Preclinical and clinical studies demonstrate that T cell‐dependent bispecific antibodies (TDBs) induce systemic changes in addition to tumor killing, leading to adverse events. Here, we report an in‐depth characterization of acute responses to TDBs in tumor‐bearing mice. Contrary to modest changes i...

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Detalles Bibliográficos
Autores principales: Himmels, Patricia, Nguyen, Thi Thu Thao, Mitzner, Maresa Caunt, Arrazate, Alfonso, Yeung, Stacey, Burton, Jeremy, Clark, Robyn, Totpal, Klara, Jesudason, Raj, Yang, Angela, Solon, Margaret, Eastham, Jeffrey, Modrusan, Zora, Webster, Joshua D, Lo, Amy A, Piskol, Robert, Ye, Weilan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986820/
https://www.ncbi.nlm.nih.gov/pubmed/36621885
http://dx.doi.org/10.15252/embr.202255532

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986820/
https://www.ncbi.nlm.nih.gov/pubmed/36621885
http://dx.doi.org/10.15252/embr.202255532

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