Multinucleation resets human macrophages for specialized functions at the expense of their identity

Macrophages undergo plasma membrane fusion and cell multinucleation to form multinucleated giant cells (MGCs) such as osteoclasts in bone, Langhans giant cells (LGCs) as part of granulomas or foreign‐body giant cells (FBGCs) in reaction to exogenous material. How multinucleation per se contributes t...

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Detalles Bibliográficos
Autores principales: Ahmadzadeh, Kourosh, Pereira, Marie, Vanoppen, Margot, Bernaerts, Eline, Ko, Jeong‐Hun, Mitera, Tania, Maksoudian, Christy, Manshian, Bella B, Soenen, Stefaan, Rose, Carlos D, Matthys, Patrick, Wouters, Carine, Behmoaras, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986822/
https://www.ncbi.nlm.nih.gov/pubmed/36597777
http://dx.doi.org/10.15252/embr.202256310

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986822/
https://www.ncbi.nlm.nih.gov/pubmed/36597777
http://dx.doi.org/10.15252/embr.202256310

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