Heterotypic electrostatic interactions control complex phase separation of tau and prion into multiphasic condensates and co-aggregates

Biomolecular condensates formed via phase separation of proteins and nucleic acids are thought to perform a wide range of critical cellular functions by maintaining spatiotemporal regulation and organizing intracellular biochemistry. However, aberrant phase transitions are implicated in a multitude...

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Detalles Bibliográficos
Autores principales: Rai, Sandeep K., Khanna, Roopali, Avni, Anamika, Mukhopadhyay, Samrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986828/
https://www.ncbi.nlm.nih.gov/pubmed/36595668
http://dx.doi.org/10.1073/pnas.2216338120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986828/
https://www.ncbi.nlm.nih.gov/pubmed/36595668
http://dx.doi.org/10.1073/pnas.2216338120

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