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Heterotypic electrostatic interactions control complex phase separation of tau and prion into multiphasic condensates and co-aggregates
Biomolecular condensates formed via phase separation of proteins and nucleic acids are thought to perform a wide range of critical cellular functions by maintaining spatiotemporal regulation and organizing intracellular biochemistry. However, aberrant phase transitions are implicated in a multitude...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9986828/ https://www.ncbi.nlm.nih.gov/pubmed/36595668 http://dx.doi.org/10.1073/pnas.2216338120 |