Novel, thalidomide-like, non-cereblon binding drug tetrafluorobornylphthalimide mitigates inflammation and brain injury

BACKGROUND: Quelling microglial-induced excessive neuroinflammation is a potential treatment strategy across neurological disorders, including traumatic brain injury (TBI), and can be achieved by thalidomide-like drugs albeit this approved drug class is compromised by potential teratogenicity. Tetra...

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Detalles Bibliográficos
Autores principales: Lecca, Daniela, Hsueh, Shih-Chang, Luo, Weiming, Tweedie, David, Kim, Dong Seok, Baig, Abdul Mannan, Vargesson, Neil, Kim, Yu Kyung, Hwang, Inho, Kim, Sun, Hoffer, Barry J., Chiang, Yung-Hsiao, Greig, Nigel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987061/
https://www.ncbi.nlm.nih.gov/pubmed/36872339
http://dx.doi.org/10.1186/s12929-023-00907-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987061/
https://www.ncbi.nlm.nih.gov/pubmed/36872339
http://dx.doi.org/10.1186/s12929-023-00907-5

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