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Long-term administration of Western diet induced metabolic syndrome in mice and causes cardiac microvascular dysfunction, cardiomyocyte mitochondrial damage, and cardiac remodeling involving caveolae and caveolin-1 expression

BACKGROUND: Long-term consumption of an excessive fat and sucrose diet (Western diet, WD) has been considered a risk factor for metabolic syndrome (MS) and cardiovascular disease. Caveolae and caveolin-1 (CAV-1) proteins are involved in lipid transport and metabolism. However, studies investigating...

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Detalles Bibliográficos
Autores principales: Liu, I.-Fan, Lin, Tzu-Chieh, Wang, Shu-Chi, Yen, Chia-Hung, Li, Chia-Yang, Kuo, Hsuan-Fu, Hsieh, Chong-Chao, Chang, Chia-Yuan, Chang, Chuang-Rung, Chen, Yung-Hsiang, Liu, Yu-Ru, Lee, Tsung-Ying, Huang, Chi-Yuan, Hsu, Chih-Hsin, Lin, Shing-Jong, Liu, Po-Len
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987103/
https://www.ncbi.nlm.nih.gov/pubmed/36879344
http://dx.doi.org/10.1186/s13062-023-00363-z