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Characterization of bone marrow heterogeneity in NK-AML (M4/M5) based on single-cell RNA sequencing

Normal karyotype acute myeloid leukemia (NK-AML) is a heterogeneous hematological malignancy that contains a minor population of self-renewing leukemia stem cells (LSCs), which complicate efforts to achieve long-term survival. We performed single-cell RNA sequencing to profile 39,288 cells from 6 bo...

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Detalles Bibliográficos
Autores principales: Wu, Wenqi, Shi, Zeyan, Tang, Zhongyuan, Li, Huiqun, Huang, Xiaoke, Liang, Xiaolin, Li, Jing, Yao, Yibin, Zhao, Weihua, Wu, Meiqing, Luo, Jun, Liu, Zhenfang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987113/
https://www.ncbi.nlm.nih.gov/pubmed/36879313
http://dx.doi.org/10.1186/s40164-023-00391-5