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Age-related accumulation of B-1 cell progenitors in mice reflects changes in miR15a/16-1 expression and radioresistance capacity

Hyperproliferative diseases such as Chronic Lymphocytic Leukemia (CLL) and Systemic Lupus Erythematosus (SLE) are potentially related to some disturbance in the apoptosis pathway, specifically in B-1a cells (CD5(+)). Accumulation of B-1a cells in lymphoid organs, bone marrow or periphery is observed...

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Detalles Bibliográficos
Autores principales: Souza, Olívia F, de Oliveira, Vivian C, Rodrigues, Gabriel J. F., Costa, Lucas V. S., Corado, Fernanda, Popi, Ana F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987129/
https://www.ncbi.nlm.nih.gov/pubmed/36879336
http://dx.doi.org/10.1186/s40164-023-00390-6