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Peripherally restricted oxytocin is sufficient to reduce food intake and motivation, while CNS entry is required for locomotor and taste avoidance effects

OBJECTIVES: Oxytocin (OT) has a well‐established role in reproductive behaviours; however, it recently emerged as an important regulator of energy homeostasis. In addition to central nervous system (CNS), OT is found in the plasma and OT receptors (OT‐R) are found in peripheral tissues relevant to e...

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Detalles Bibliográficos
Autores principales: Asker, Mohammed, Krieger, Jean‐Philippe, Liles, Amber, Tinsley, Ian C., Borner, Tito, Maric, Ivana, Doebley, Sarah, Furst, C. Daniel, Börchers, Stina, Longo, Francesco, Bhat, Yashaswini R., De Jonghe, Bart C., Hayes, Matthew R., Doyle, Robert P., Skibicka, Karolina P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9987651/
https://www.ncbi.nlm.nih.gov/pubmed/36495318
http://dx.doi.org/10.1111/dom.14937