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Estrogen/Progesterone Receptor Loss, CTNNB1 and KRAS Mutations Are Associated With Local Recurrence or Distant Metastasis in Low-Grade Endometrial Endometrioid Carcinoma

A subset of endometrial endometrioid carcinomas (EECs) with low-grade histology recur with poor outcomes. Published evidence suggests that poor outcomes may be associated with loss of expression of ER-alpha (ER-α) as well as with β-Catenin-1 (CTNNB1) and Kirsten rat sarcoma viral oncogene homolog (K...

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Detalles Bibliográficos
Autores principales: Chibbar, Rajni, Foerstner, Sabrina, Suresh, Janarathnee, Chibbar, Richa, Piche, Alexandre, Kundapur, Deeksha, Kanthan, Rani, Kundapur, Vijayanand, Lee, Cheng Han, Agrawal, Anita, Lai, Raymond
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988232/
https://www.ncbi.nlm.nih.gov/pubmed/36695555
http://dx.doi.org/10.1097/PAI.0000000000001102