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Redox regulation of K(V)7 channels through EF3 hand of calmodulin

Neuronal K(V)7 channels, important regulators of cell excitability, are among the most sensitive proteins to reactive oxygen species. The S2S3 linker of the voltage sensor was reported as a site-mediating redox modulation of the channels. Recent structural insights reveal potential interactions betw...

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Detalles Bibliográficos
Autores principales: Nuñez, Eider, Jones, Frederick, Muguruza-Montero, Arantza, Urrutia, Janire, Aguado, Alejandra, Malo, Covadonga, Bernardo-Seisdedos, Ganeko, Domene, Carmen, Millet, Oscar, Gamper, Nikita, Villarroel, Alvaro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988260/
https://www.ncbi.nlm.nih.gov/pubmed/36803414
http://dx.doi.org/10.7554/eLife.81961