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eIg-based bispecific T-cell engagers targeting EGFR: Format matters

Bispecific antibodies are molecules with versatile modes of action and applications for therapy. They are commonly developed as T-cell engagers (TCE), which simultaneously target an antigen expressed by tumor cells and CD3 expressed by T-cells, thereby inducing T-cell-mediated target cell killing. T...

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Detalles Bibliográficos
Autores principales: Kühl, Lennart, Schäfer, Annelie K., Kraft, Sebastian, Aschmoneit, Nadine, Kontermann, Roland E., Seifert, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988351/
https://www.ncbi.nlm.nih.gov/pubmed/36864566
http://dx.doi.org/10.1080/19420862.2023.2183540