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Deregulation of the cyclin-dependent kinase inhibitor p27 as a putative candidate for transformation in Chlamydia trachomatis infected mesenchymal stem cells

PURPOSE: Several pathological conditions might cause the degradation of the cyclin-dependent kinase inhibitor (CKI) p27 and cell cycle arrest at the G1 phase, including cancers and infections. Chlamydia trachomatis (Ctr), as an obligatory intracellular pathogen, has been found to alter the fate of t...

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Detalles Bibliográficos
Autores principales: Abu-Lubad, Mohammad A., Al-Zereini, Wael, Al-Zeer, Munir A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIMS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988407/
https://www.ncbi.nlm.nih.gov/pubmed/36891539
http://dx.doi.org/10.3934/microbiol.2023009