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In vitro and in silico evaluation of antiretrovirals against SARS-CoV-2: A drug repurposing approach

BACKGROUND: Drug repurposing is a valuable strategy for rapidly developing drugs for treating COVID-19. This study aimed to evaluate the antiviral effect of six antiretrovirals against SARS-CoV-2 in vitro and in silico. METHODS: The cytotoxicity of lamivudine, emtricitabine, tenofovir, abacavir, efa...

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Detalles Bibliográficos
Autores principales: Zapata-Cardona, Maria I., Florez-Alvarez, Lizdany, Guerra-Sandoval, Ariadna L., Chvatal-Medina, Mateo, Guerra-Almonacid, Carlos M., Hincapie-Garcia, Jaime, Hernandez, Juan C., Rugeles, Maria T., Zapata-Builes, Wildeman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIMS Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988408/
https://www.ncbi.nlm.nih.gov/pubmed/36891537
http://dx.doi.org/10.3934/microbiol.2023002