Usefulness of a humanized tricellular static transwell blood–brain barrier model as a microphysiological system for drug development applications. - A case study based on the benchmark evaluations of blood-brain barrier microphysiological system

Microphysiological system (MPS), a new technology for in vitro testing platforms, have been acknowledged as a strong tool for drug development. In the central nervous system (CNS), the blood‒brain barrier (BBB) limits the permeation of circulating substances from the blood vessels to the brain, ther...

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Detalles Bibliográficos
Autores principales: Nakayama-Kitamura, Kimiko, Shigemoto-Mogami, Yukari, Toyoda, Hiroko, Mihara, Ikue, Moriguchi, Hiroyuki, Naraoka, Hitoshi, Furihata, Tomomi, Ishida, Seiichi, Sato, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society for Regenerative Medicine 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988422/
https://www.ncbi.nlm.nih.gov/pubmed/36891355
http://dx.doi.org/10.1016/j.reth.2023.02.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988422/
https://www.ncbi.nlm.nih.gov/pubmed/36891355
http://dx.doi.org/10.1016/j.reth.2023.02.001

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