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Development and validation of a novel HPLC-UV method for simultaneous determination of azathioprine metabolites in human red blood cells

A rapid, specific and accurate high-performance liquid chromatography with tunable ultraviolet detection method was developed to simultaneously determine azathioprine metabolites, 6-thioguanine nucleotides (6-TGN) and 6-methyl mercaptopurine riboside (6-MMPr) in human red blood cells. Erythrocyte ly...

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Detalles Bibliográficos
Autores principales: Yu, Hengyi, Li, Dongyan, Xiang, Dong, Li, Xiping, Liu, Lu, Liu, Dong, Gong, Xuepeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988558/
https://www.ncbi.nlm.nih.gov/pubmed/36895397
http://dx.doi.org/10.1016/j.heliyon.2023.e13870