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Identifying multiscale translational safety biomarkers using a network-based systems approach

Animal testing is the current standard for drug and chemicals safety assessment, but hazards translation to human is uncertain. Human in vitro models can address the species translation but might not replicate in vivo complexity. Herein, we propose a network-based method addressing these translation...

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Detalles Bibliográficos
Autores principales: Callegaro, Giulia, Schimming, Johannes P., Piñero González, Janet, Kunnen, Steven J., Wijaya, Lukas, Trairatphisan, Panuwat, van den Berk, Linda, Beetsma, Kim, Furlong, Laura I., Sutherland, Jeffrey J., Mollon, Jennifer, Stevens, James L., van de Water, Bob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988559/
https://www.ncbi.nlm.nih.gov/pubmed/36895646
http://dx.doi.org/10.1016/j.isci.2023.106094