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The well-developed actin cytoskeleton and Cthrc1 expression by actin-binding protein drebrin in myofibroblasts promote cardiac and hepatic fibrosis

Fibrosis is mainly triggered by inflammation in various tissues, such as heart and liver tissues, and eventually leads to their subsequent dysfunction. Fibrosis is characterized by the excessive accumulation of extracellular matrix proteins (e.g., collagens) produced by myofibroblasts. The well-deve...

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Detalles Bibliográficos
Autores principales: Hironaka, Takanori, Takizawa, Noburo, Yamauchi, Yuto, Horii, Yuma, Nakaya, Michio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988570/
https://www.ncbi.nlm.nih.gov/pubmed/36690273
http://dx.doi.org/10.1016/j.jbc.2023.102934