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Inhalable aerosol microparticles with low carrier dosage and high fine particle fraction prepared by spray-freeze-drying
Co-suspension drug-loading technology, namely Aerosphere™, can improve fine particle fraction (FPF) and delivered dose content uniformity (DDCU). However, because of its poor drug-loading efficacy, the phospholipid carrier dosage in Aerosphere™ is usually dozens of times greater than that of the dru...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988654/ https://www.ncbi.nlm.nih.gov/pubmed/36896094 http://dx.doi.org/10.1016/j.ijpx.2023.100158 |