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Targeting the metastatic niche: Single-cell lineage tracing in prime time
Identification of actionable drug targets remains a rate-limiting step of, and one of the most prominent barriers to successful drug development for metastatic cancers. CRISPR-Cas9, a tool for making targeted genomic edits, has given rise to various novel applications that have greatly accelerated d...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988656/ https://www.ncbi.nlm.nih.gov/pubmed/36895653 http://dx.doi.org/10.1016/j.isci.2023.106174 |