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Targeting the metastatic niche: Single-cell lineage tracing in prime time

Identification of actionable drug targets remains a rate-limiting step of, and one of the most prominent barriers to successful drug development for metastatic cancers. CRISPR-Cas9, a tool for making targeted genomic edits, has given rise to various novel applications that have greatly accelerated d...

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Detalles Bibliográficos
Autores principales: Sommer, Elijah R., Napoli, Giulia C., Chau, Cindy H., Price, Douglas K., Figg, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988656/
https://www.ncbi.nlm.nih.gov/pubmed/36895653
http://dx.doi.org/10.1016/j.isci.2023.106174