Celastrol Alleviates Corneal Stromal Fibrosis by Inhibiting TGF-β1/Smad2/3-YAP/TAZ Signaling After Descemet Stripping Endothelial Keratoplasty

PURPOSE: The purpose of this study was to investigate the effect of celastrol (CEL) on corneal stromal fibrosis after Descemet stripping endothelial keratoplasty (DSEK) and its associated mechanism. METHODS: Rabbit corneal fibroblasts (RCFs) were isolated, cultured, and identified. A CEL-loaded posi...

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Detalles Bibliográficos
Autores principales: Liu, Ruixing, Li, Jingguo, Guo, Zhihua, Chu, Dandan, Li, Chengcheng, Shi, Liuqi, Zhang, Junjie, Zhu, Lei, Li, Zhanrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2023
Materias:
Cornea
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988716/
https://www.ncbi.nlm.nih.gov/pubmed/36867128
http://dx.doi.org/10.1167/iovs.64.3.9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988716/
https://www.ncbi.nlm.nih.gov/pubmed/36867128
http://dx.doi.org/10.1167/iovs.64.3.9

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