Cargando…

Celastrol Alleviates Corneal Stromal Fibrosis by Inhibiting TGF-β1/Smad2/3-YAP/TAZ Signaling After Descemet Stripping Endothelial Keratoplasty

PURPOSE: The purpose of this study was to investigate the effect of celastrol (CEL) on corneal stromal fibrosis after Descemet stripping endothelial keratoplasty (DSEK) and its associated mechanism. METHODS: Rabbit corneal fibroblasts (RCFs) were isolated, cultured, and identified. A CEL-loaded posi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Liu, Ruixing, Li, Jingguo, Guo, Zhihua, Chu, Dandan, Li, Chengcheng, Shi, Liuqi, Zhang, Junjie, Zhu, Lei, Li, Zhanrong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2023
Materias:	Cornea
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988716/ https://www.ncbi.nlm.nih.gov/pubmed/36867128 http://dx.doi.org/10.1167/iovs.64.3.9

Ejemplares similares

Celastrol-based nanomedicine promotes corneal allograft survival
por: Li, Zhanrong, et al.
Publicado: (2021)

Surgical outcome of Descemet’s stripping automated endothelial keratoplasty for bullous keratopathy secondary to argon laser iridotomy
por: Hirayama, Masatoshi, et al.
Publicado: (2012)

Femtosecond laser semi-assisted Descemet stripping endothelial keratoplasty: 2-year outcomes of endothelial cell loss and graft survival
por: Wang, Ting, et al.
Publicado: (2021)

Descemet membrane endothelial keratoplasty compared with ultrathin Descemet stripping automated endothelial keratoplasty: a meta-analysis
por: Sela, Tal Corina, et al.
Publicado: (2023)

Graft survival of Descemet membrane endothelial keratoplasty (DMEK) in corneal endothelial decompensation after glaucoma surgery
por: Schrittenlocher, Silvia, et al.
Publicado: (2021)

Retinometer predicts visual outcome in Descemet membrane endothelial keratoplasty
por: Wald, Caroline Sophie, et al.
Publicado: (2022)

Effects of uncomplicated Descemet membrane endothelial keratoplasty on the central retinal thickness
por: Lohmann, Tibor, et al.
Publicado: (2021)

Descemet membrane endothelial keratoplasty (DMEK) improves vision-related quality of life
por: Gellert, Alexandra, et al.
Publicado: (2022)

Descemet's Membrane Modulation of Posterior Corneal Fibrosis
por: Medeiros, Carla S., et al.
Publicado: (2019)

Descemet membrane endothelial keratoplasty (DMEK): clinical results of precut versus surgeon-cut grafts
por: Koechel, Doreen, et al.
Publicado: (2020)

Graft failure rate and complications after Descemet membrane endothelial keratoplasty in eyes with pre-existing glaucoma
por: Maier, Anna-Karina B., et al.
Publicado: (2022)

Outcomes after Descemet membrane endothelial keratoplasty over a period of 7 years at a tertiary referral center: endothelial cell density, central corneal thickness, and visual acuity
por: Bayyoud, Tarek, et al.
Publicado: (2021)

Cigarette Smoke Triggers Loss of Corneal Endothelial Cells and Disruption of Descemet's Membrane Proteins in Mice
por: Ali, Muhammad, et al.
Publicado: (2021)

Early changes in host and donor lenticule thickness after Descemet stripping endothelial keratoplasty
por: Yien, Bandana, et al.
Publicado: (2022)

Mice Deficient in TAZ (Wwtr1) Demonstrate Clinical Features of Late-Onset Fuchs’ Endothelial Corneal Dystrophy
por: Leonard, Brian C., et al.
Publicado: (2023)

Cost-effectiveness of Descemet stripping automated endothelial keratoplasty versus penetrating keratoplasty in patients with endothelial dysfunction in India
por: Shah, Pooja, et al.
Publicado: (2021)

Visual Outcomes of Ultrathin-Descemet Stripping Endothelial Keratoplasty versus Descemet Stripping Endothelial Keratoplasty
por: Droutsas, Konstantinos, et al.
Publicado: (2018)

Recurrence of perforation and overall patient survival after penetrating keratoplasty versus amniotic membrane transplantation in corneal perforation
por: Elhardt, Carolin, et al.
Publicado: (2023)

Outcomes of Descemet stripping endothelial keratoplasty in cases of corneal endothelial dysfunction
por: Srujana, Dubbaka, et al.
Publicado: (2022)

Erratum to “Visual Outcomes of Ultrathin-Descemet Stripping Endothelial Keratoplasty versus Descemet Stripping Endothelial Keratoplasty”
por: Droutsas, Konstantinos, et al.
Publicado: (2019)

Viability of preloaded Descemet membrane endothelial keratoplasty grafts with 96-hour shipment
por: Chen, Conan, et al.
Publicado: (2021)

Preferred practice pattern for Descemet membrane endothelial keratoplasty surgeries: A survey of Indian corneal surgeons
por: Sahay, Pranita, et al.
Publicado: (2022)

Descemet stripping automated endothelial keratoplasty
por: Sharma, Namrata, et al.
Publicado: (2017)

Agrin Promotes Limbal Stem Cell Proliferation and Corneal Wound Healing Through Hippo-Yap Signaling Pathway
por: Hou, Lulu, et al.
Publicado: (2020)

Outcomes of rebubbling for graft detachment after Descemet's stripping endothelial keratoplasty or Descemet's stripping automated endothelial keratoplasty
por: Bhalerao, Sushank A, et al.
Publicado: (2020)

Effectively suppressed angiogenesis-mediated retinoblastoma growth using celastrol nanomicelles
por: Li, Zhanrong, et al.
Publicado: (2020)

Atypical presentation of macular corneal dystrophy managed by Descemet stripping endothelial keratoplasty
por: Chaurasia, Sunita, et al.
Publicado: (2019)

Systemic immunosuppression with mycophenolate mofetil to prevent corneal graft rejection after high-risk penetrating keratoplasty: a 2-year follow-up study
por: Szaflik, Jacek P., et al.
Publicado: (2015)

Celastrol nanoparticles inhibit corneal neovascularization induced by suturing in rats
por: Li, Zhanrong, et al.
Publicado: (2012)

Repeat keratoplasty in failed Descemet stripping automated endothelial keratoplasty
por: Kaur, Manpreet, et al.
Publicado: (2019)

Topographic characteristics after Descemet’s membrane endothelial keratoplasty and Descemet’s stripping automated endothelial keratoplasty
por: Hayashi, Takahiko, et al.
Publicado: (2017)

Descemet Stripping Automated Endothelial Keratoplasty in Thick Corneas
por: Li, Chendi, et al.
Publicado: (2022)

Macrostriae and Descemet's membrane folds in the Descemet's stripping endothelial keratoplasty graft
por: Turaka, Kiran, et al.
Publicado: (2011)

Eye bank versus surgeon prepared Descemet stripping automated endothelial keratoplasty tissues: Influence on adhesion force in a pilot study
por: Romano, Vito, et al.
Publicado: (2022)

Donor cross-linking for keratoplasty: a laboratory evaluation
por: Mukherjee, Achyut, et al.
Publicado: (2015)

Non-Descemet stripping automated endothelial keratoplasty for post radial keratotomy corneal edema
por: Shah, Sushmita Gaurav, et al.
Publicado: (2018)

Evaluation of interface reflectivity and corneal aberrations following Descemet's stripping automated endothelial keratoplasty
por: Khakshour, Hamid, et al.
Publicado: (2019)

Descemet stripping endothelial keratoplasty after cytomegalovirus corneal endotheliitis and immunosuppression for Mooren's ulcer
por: Ueda, Koji, et al.
Publicado: (2021)

Outcome of Descemet membrane endothelial keratoplasty for graft failure after Descemet stripping automated endothelial keratoplasty
por: Agha, Bishr, et al.
Publicado: (2019)

Outcome of Descemet Stripping Automated Endothelial Keratoplasty in Failed Penetrating Keratoplasty
por: Khairallah, Abdulrahman S.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_j9mt1o5rgn165l3fpf138aqacr