High-throughput Pore-C reveals the single-allele topology and cell type-specificity of 3D genome folding

Canonical three-dimensional (3D) genome structures represent the ensemble average of pairwise chromatin interactions but not the single-allele topologies in populations of cells. Recently developed Pore-C can capture multiway chromatin contacts that reflect regional topologies of single chromosomes....

Descripción completa

Detalles Bibliográficos
Autores principales: Zhong, Jia-Yong, Niu, Longjian, Lin, Zhuo-Bin, Bai, Xin, Chen, Ying, Luo, Feng, Hou, Chunhui, Xiao, Chuan-Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988853/
https://www.ncbi.nlm.nih.gov/pubmed/36878904
http://dx.doi.org/10.1038/s41467-023-36899-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988853/
https://www.ncbi.nlm.nih.gov/pubmed/36878904
http://dx.doi.org/10.1038/s41467-023-36899-x

Ejemplares similares