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High-throughput Pore-C reveals the single-allele topology and cell type-specificity of 3D genome folding
Canonical three-dimensional (3D) genome structures represent the ensemble average of pairwise chromatin interactions but not the single-allele topologies in populations of cells. Recently developed Pore-C can capture multiway chromatin contacts that reflect regional topologies of single chromosomes....
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988853/ https://www.ncbi.nlm.nih.gov/pubmed/36878904 http://dx.doi.org/10.1038/s41467-023-36899-x |