Polynitroxylated PEGylated hemoglobin protects pig brain neocortical gray and white matter after traumatic brain injury and hemorrhagic shock

Polynitroxylated PEGylated hemoglobin (PNPH, aka SanFlow) possesses superoxide dismutase/catalase mimetic activities that may directly protect the brain from oxidative stress. Stabilization of PNPH with bound carbon monoxide prevents methemoglobin formation during storage and permits it to serve as...

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Detalles Bibliográficos
Autores principales: Wang, Jun, Shi, Yanrong, Cao, Suyi, Liu, Xiuyun, Martin, Lee J., Simoni, Jan, Soltys, Bohdan J., Hsia, Carleton J. C., Koehler, Raymond C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Medical Technology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988926/
https://www.ncbi.nlm.nih.gov/pubmed/36896342
http://dx.doi.org/10.3389/fmedt.2023.1074643

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988926/
https://www.ncbi.nlm.nih.gov/pubmed/36896342
http://dx.doi.org/10.3389/fmedt.2023.1074643

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