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Polynitroxylated PEGylated hemoglobin protects pig brain neocortical gray and white matter after traumatic brain injury and hemorrhagic shock
Polynitroxylated PEGylated hemoglobin (PNPH, aka SanFlow) possesses superoxide dismutase/catalase mimetic activities that may directly protect the brain from oxidative stress. Stabilization of PNPH with bound carbon monoxide prevents methemoglobin formation during storage and permits it to serve as...
Autores principales: | Wang, Jun, Shi, Yanrong, Cao, Suyi, Liu, Xiuyun, Martin, Lee J., Simoni, Jan, Soltys, Bohdan J., Hsia, Carleton J. C., Koehler, Raymond C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988926/ https://www.ncbi.nlm.nih.gov/pubmed/36896342 http://dx.doi.org/10.3389/fmedt.2023.1074643 |
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