Reprogramming of palmitic acid induced by dephosphorylation of ACOX1 promotes β-catenin palmitoylation to drive colorectal cancer progression

Metabolic reprogramming is a hallmark of cancer. However, it is not well known how metabolism affects cancer progression. We identified that metabolic enzyme acyl-CoA oxidase 1 (ACOX1) suppresses colorectal cancer (CRC) progression by regulating palmitic acid (PA) reprogramming. ACOX1 is highly down...

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Detalles Bibliográficos
Autores principales: Zhang, Qiang, Yang, Xiaoya, Wu, Jinjie, Ye, Shubiao, Gong, Junli, Cheng, Wai Ming, Luo, Zhanhao, Yu, Jing, Liu, Yugeng, Zeng, Wanyi, Liu, Chen, Xiong, Zhizhong, Chen, Yuan, He, Zhen, Lan, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Nature Singapore 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988979/
https://www.ncbi.nlm.nih.gov/pubmed/36878899
http://dx.doi.org/10.1038/s41421-022-00515-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9988979/
https://www.ncbi.nlm.nih.gov/pubmed/36878899
http://dx.doi.org/10.1038/s41421-022-00515-x

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