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How Applicable Is the Single-Dose AMBITION Regimen for Human Immunodeficiency Virus–Associated Cryptococcal Meningitis to High-Income Settings?

The AmBisome Therapy Induction Optimization (AMBITION-cm) trial, conducted in eastern and southern Africa, showed that a single, high dose (10 mg/kg) of liposomal amphotericin B, given with an oral backbone of fluconazole and flucytosine, was noninferior to the World Health Organization (WHO)–recomm...

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Detalles Bibliográficos
Autores principales: Harrison, Thomas S, Lawrence, David S, Mwandumba, Henry C, Boulware, David R, Hosseinipour, Mina C, Lortholary, Olivier, Meintjes, Graeme, Mosepele, Mosepele, Jarvis, Joseph N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989135/
https://www.ncbi.nlm.nih.gov/pubmed/36166405
http://dx.doi.org/10.1093/cid/ciac792