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Probing the relevance of the accelerated aging mouse line SAMP8 as a model for certain types of neuropsychiatric symptoms in dementia

INTRODUCTION: People with dementia (PwD) often present with neuropsychiatric symptoms (NPS). NPS are of substantial burden to the patients, and current treatment options are unsatisfactory. Investigators searching for novel medications need animal models that present disease-relevant phenotypes and...

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Detalles Bibliográficos
Autores principales: Bergamini, Giorgio, Massinet, Helene, Hart, Aaron, Durkin, Sean, Pierlot, Gabin, Steiner, Michel Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989166/
https://www.ncbi.nlm.nih.gov/pubmed/36896346
http://dx.doi.org/10.3389/fpsyt.2023.1054163