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Distinctive modulation of hepcidin in cancer and its therapeutic relevance

Hepcidin, a short peptide synthesized primarily by hepatocytes in response to increased body iron and inflammation, is a crucial iron-regulating factor. Hepcidin regulates intestinal iron absorption and releases iron from macrophages into plasma through a negative iron feedback mechanism. The discov...

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Detalles Bibliográficos
Autores principales: Lin, Feng, Tuffour, Alex, Hao, Guijie, Peprah, Frank Addai, Huang, Aixia, Zhou, Yang, Zhang, Haiqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989193/
https://www.ncbi.nlm.nih.gov/pubmed/36895478
http://dx.doi.org/10.3389/fonc.2023.1141603