Learned features of antibody-antigen binding affinity

Defining predictors of antigen-binding affinity of antibodies is valuable for engineering therapeutic antibodies with high binding affinity to their targets. However, this task is challenging owing to the huge diversity in the conformations of the complementarity determining regions of antibodies an...

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Detalles Bibliográficos
Autores principales: Miller, Nathaniel L., Clark, Thomas, Raman, Rahul, Sasisekharan, Ram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989197/
https://www.ncbi.nlm.nih.gov/pubmed/36895805
http://dx.doi.org/10.3389/fmolb.2023.1112738

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989197/
https://www.ncbi.nlm.nih.gov/pubmed/36895805
http://dx.doi.org/10.3389/fmolb.2023.1112738

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