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Learned features of antibody-antigen binding affinity

Defining predictors of antigen-binding affinity of antibodies is valuable for engineering therapeutic antibodies with high binding affinity to their targets. However, this task is challenging owing to the huge diversity in the conformations of the complementarity determining regions of antibodies an...

תיאור מלא

מידע ביבליוגרפי
Autores principales: Miller, Nathaniel L., Clark, Thomas, Raman, Rahul, Sasisekharan, Ram
פורמט: Online Artículo Texto
שפה:English
יצא לאור: Frontiers Media S.A. 2023
נושאים:
גישה מקוונת:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989197/
https://www.ncbi.nlm.nih.gov/pubmed/36895805
http://dx.doi.org/10.3389/fmolb.2023.1112738