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Learned features of antibody-antigen binding affinity

Defining predictors of antigen-binding affinity of antibodies is valuable for engineering therapeutic antibodies with high binding affinity to their targets. However, this task is challenging owing to the huge diversity in the conformations of the complementarity determining regions of antibodies an...

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Dettagli Bibliografici
Autori principali: Miller, Nathaniel L., Clark, Thomas, Raman, Rahul, Sasisekharan, Ram
Natura: Online Articolo testo
Lingua:English
Pubblicazione: Frontiers Media S.A. 2023
Soggetti:
Accesso online:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9989197/
https://www.ncbi.nlm.nih.gov/pubmed/36895805
http://dx.doi.org/10.3389/fmolb.2023.1112738